WINNER AMEC Award Medical Research (Paris 2016)
WINNER AMEC Award Medical Research (Paris 2016)
Wound healing, especially impending skin necrosis is a subject of ever increasing interest to the aesthetic industry due to the ever-increasing use of dermal fillers in facial rejuvenation. While much of the physiology of wound healing is understood, gaps still exist in our understanding of the phenomenon, especially that of trying to promote epithelial formation to prevent further dermal scarring when vascular occlusion occurs. Physicians to date have not focused on the outer layer of skin to modify the wound milieu. It has been known for some time that hypoxia is a vital stimulant for angiogenesis and consequent dermal development, but development of adequate capillary network post vascular occlusion requires adequate amounts of tissue oxygen concentration. The research team used hyperbaric oxygen (HBOT) in conjunction with weekly platelet-rich plasma (PRP) and daily 633nm low-level laser therapy (LLLT) to regenerate epithelial tissue.

